Here are five talking points from the weekend's action:
Christian Benteke headed home from close range as Liverpool grabbed a stoppage-time leveller to snatch a point against Chelsea in a 1-1 draw on Wednesday after Eden Hazard's dazzling opener for the visitors.
Manchester United play Liverpool at Old Trafford and Chelsea face Arsenal at Stamford Bridge on Sunday.
Following is a match by match look at the English Premier League's weekend fixtures:
ManchesterCity and Manchester United scored 10 goals between them and boosted their title aspirations with convincing wins over NorwichCity and Fulham respectively on an eventful afternoon in the Premier League on Saturday.
Tottenham Hotspur's status as Premier League title chasers was seriously harmed on Saturday as they fell to a first defeat in seven league games, losing the lead to go down 3-1 at home to Wolverhampton Wanderers.
A stunning late strike from red-hot Tottenham Hotspur winger Gareth Bale lifted the Londoners to a 3-2 win over West Ham United on Monday that took them up to third in the Premier League table.
Arsenal and Manchester City meet at The Emirates on Saturday when both teams will seek to roar into life after making spluttering starts to their Premier League campaigns.
Images from the English Premier League matches played at Old Trafford on Saturday
City have 89 points, one more than rivals Liverpool, with both teams having three games to play -- and none of them against top six opponents.
Juergen Klopp's side, chasing their maiden title in the Premier League era and first in the top flight in 30 years, took a 14th-minute lead from a Virgil van Dijk header but had to wait until stoppage time to put the game to bed through Mohamed Salah.
Manchester City's impressive 2-0 victory at Everton on Sunday equalled a club record of nine successive Premier League wins.
Jose Mourinho's reshaped Manchester United destroyed Premier League champions Leicester City 4-1 with a performance that thrilled Old Trafford on Saturday and justified his decision to leave out Wayne Rooney. The shake-up seemed to liberate Paul Pogba who led the way with a polished display, heading his first goal for the club on 42 minutes and starting the clever move that led to Juan Mata firing home United's second after 37 minutes.
Frank Lampard's loan spell at Manchester City is due to end in January but the Premier League champions might want to delay his departure across the Atlantic to enhance their chances of fighting his old club for the title.
Liverpool opened up an eight-point lead at the top of the Premier League with an emphatic and hugely impressive 3-1 win over defending champions Manchester City.
Arsenal maintained their challenge for a first trophy in nine seasons when they beat Liverpool 2-0 at the Emirates Stadium to open up a five-point lead at the top of the Premier League on Saturday.
Newcastle United continued their push for Europa League football next season when two excellent goals from Papiss Cisse and a superb strike from Hatem ben Arfa gave them a 3-1 win at West Bromwich Albion in the Premier League on Sunday.
Arsenal's faint hopes of winning the Premier League title were finally killed off when Wigan Athletic scored three goals in the last 10 minutes to snatch a dramatic 3-2 victory on Sunday.
The momentum that swept Leicester City away from relegation last season continued unabated at West Ham United on Saturday as their 2-1 win left them top of the Premier League.
Champions Manchester United will travel to Swansea City for their first Premier League match under new manager David Moyes while Manuel Pellegrini's Manchester City are at home to Newcastle United on August 17.
Photos and summary of the English Premier League matches played on Tuesday, including the story of Chelsea's resurgent win
Tottenham Hotspur fluffed their last-day lines with a 5-1 defeat at relegated, 10-man Newcastle United that left them third in the Premier League behind bitter north London rivals Arsenal.
Tottenham Hotspur steamed into the top four with Harry Kane marking his 100th Premier League appearance with a double in a 4-1 thrashing of Watford on Sunday.
Normally the candidates for goal of the season are spread throughout the 10 months of the campaign, but this weekend's Premier League matches produced six memorable strikes in little over 24 hours.
Four months after quitting Liverpool for Manchester City, Raheem Sterling will have the first opportunity to justify the move by getting one over his former employers when the teams meet at the Etihad Stadium on Saturday.
About 900 jubilant fans and employees of the Thai billionaire who owns Leicester City roared when the final whistle blew in their team's 1-1 draw at Manchester United.
Liverpool forward Daniel Sturridge is back in full training for the first time since injuring his thigh on England duty in August, the 25-year-old said on Twitter.
Photos from the English Premier League matches played on Wednesday.
Arsenal claimed the final Champions League spot at the expense of their arch rivals Tottenham Hotspur on the last day of the Premier League season on Sunday with a 1-0 win at Newcastle United.
Pep Guardiola finds English football 'fascinating' and his ambition is to manage a Premier League club in future, the sought-after former Barcelona coach said.
Chelsea manager Jose Mourinho should have apologised to former team doctor Eva Carneiro for his criticism of her, Football Association chairman Greg Dyke has said.
The schedule of matches in the 2010-11 English Premier LEague season.
'It's not easy to handle a team at a big, big club... always demanding to win competitions and every manager needs time. I have the feeling United started to play the way he wants'
Reading enjoyed a memorable first taste of the top flight when they beat Middlesbrough 3-2.
Tottenham's task was made all the more difficult two minutes before the interval when forward Son Heung-min was sent off
Champions Manchester United travel to Swansea City for their first Premier League match under new manager David Moyes, while Manuel Pellegrini's Manchester City are at home to Newcastle United on August 17.
Images from the English Premier League matches played on Saturday
A rampant Harry Kane netted four goals and livewire Son Heung-Min scored twice as Tottenham Hotspur thrashed Leicester City 6-1 in an action-packed Premier League clash on Thursday.
Manchester United have surpassed local rivals Manchester City in the Premier League table in terms of salary paid to their players.
Leicester City must wait at least one more day for their first-ever Premier League title after drawing 1-1 with Manchester United at Old Trafford on Sunday.